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Pol J Cosmetol 2024, 27(1): 10-14pl  Skin and appendages lesions associated with SARS-CoV-2 infectionSara Grabas, Agnieszka Garncarczyk, Agnieszka Lubczyńska, Dominika Wcisło-Dziadecka, Klaudia Mazurek, Sandra Biela-Wojtyczka, Dawid Burczyk Katedra i Zakład Kosmetologii Praktycznej i Diagnostyki Skóry, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej, Śląski Uniwersytet Medyczny w Katowicach Summary COVID-19 disease is a viral condition caused by infection with the SARS-CoV-2 virus. It started in 2019 and has since become a global health problem known as a pandemic. The main symptoms of the disease include fever, dry cough, dyspnoea, headache, muscle and joint pain. Loss of smell and taste as well as chronic fatigue are characteristic for this disease. There is also an increasing number of publications discussing manifestations located on the skin and its appendages. The disease can be variable in severity, even fatal, while its complications may persist for many weeks or months after the active viral infection is cured. This is due to the continued emergence of genetic mutations of the SARS- CoV-2 virus, and the consequent difficulty of limiting its spread. Many attempts have been made to develop vaccines or drugs as well as many sanitary restrictions have been imposed. The most commonly described skin manifestations are maculopapular, vesicular, frostbite and urticarial rashes. In turn, appendage lesions include telogen effluvium and alopecia areata as well as nail changes, namely Beau´s and Mees´s lines, red half-moon sign and transverse orange nail lesions. Protective measures and personal hygiene products contribute to the development or intensification of conditions such as acne lesions with the development of a new type of acne called ´maskne´, rosacea, seborrheic dermatitis, urticaria and contact dermatitis both allergic and resulting from irritation. The lesions demonstrated may be the only symptom of coronavirus disease and are sometimes associated with the severity of its course. Their cognition and in-depth analysis are therefore very important from a dermatological and epidemiological point of view. Many lesions have not been unequivocally characterised as a symptom of SARS-CoV-2 infection, which should prompt further research. Key words: Covid-19, SARS-CoV-2, skin, appendages, disease lesions |