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Pol J Cosmetol 2023, 26(1): 27-33pl  Mechanisms of endogenous skin agingPaulina Borowik 1/, Wioleta Faruga-Lewicka 1,2/ 1/ Śląska Wyższa Szkoła Medyczna w Katowicach 2/ Śląski Uniwersytet Medyczny w Katowicach Summary Aging is associated with cellular atrophy, slowing of repair processes, and above all, with the deterioration of the ability to perform basic physiological and biological cellular functions. It is mainly associated with an impact on the the physicochemical properties of cells and their metabolism thus impairing the the regenerative capacity of the body, as well as the processes of self-regulation. In connection with the multifactoriality of the etiopathogenesis of aging, three types can be distinguished aging, these are: intrinsic aging - mainly related to processes resulting from the passage of years; mimic aging - otherwise known as myostasis, influenced its impact is influenced by daily contractions of facial muscles, thus causing the formation of wrinkles; extrinsic aging - caused by factors that largely depend to a large extent on the daily habits and personal habits of individuals, such as as well as exposure to ultraviolet radiation. Intrinsic aging is that which is conditioned by factors endogenous, that is, those that result from factors that directly affect the the functioning and operation of the entire organism. It is also referred to by the term aging proper. This process consists of disorders related to hormonal regulation, genetics, the passage of time, the occurrence of reactive oxygen species, dehydration of the body, insufficient amounts of essential minerals and vitamins, systemic diseases, debilitating conditions, taking various types of drugs from the group of steroids, immunosuppressors, sedatives or psychotropic drugs, as well as all the biological changes taking place related to the above mentioned above. Key words: aging, wrinkles, telomeres, free radicals, estrogens |